Platelet-rich plasma, plasma rich in growth factors and simvastatin in the regeneration and repair of alveolar bone

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Platelet-rich plasma, plasma rich in growth factors and simvastatin in the regeneration and repair of alveolar bone

Platelet preparations promote bone regeneration by inducing cell migration, proliferation and differentiation in the area of the injury, which are essential processes for regeneration. In addition, several studies have indicated that simvastatin (SIMV), widely used for the treatment of hypercholesterolemia, stimulates osteogenesis. The objective of this study was to evaluate the effects of trea...

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Maxillary alveolar bone grafting: the role of Platelet-rich plasma (PRF)

Introduction: Gold standard for alveolar cleft bone grafting is autogenous bone. Advantage of adding the growth factors to the bone is established, so adding PRF to the autogenous bone may have beneficial effects. Methods:  Platelet-rich plasma admixed with autogenous bone and as a biologic membrane over the bone grafted alveolar cleft was used. Results:  Autogenous bone in all (four cases...

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ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2013

ISSN: 1792-0981,1792-1015

DOI: 10.3892/etm.2013.1327